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Testing

Axen Cancer Panel 1, cfDNA (liquid biopsy)

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The same 88-gene panel run on cell-free DNA from a blood sample, for when tissue is limited or unavailable.

Clinical purposeDetects tumour-derived variants circulating in blood. Useful when a tissue biopsy is not possible or when a less invasive sample is preferred.
Sample typeBlood (cell-free DNA)
Genes / regions covered88 genes for SNVs and indels, plus ALK, RET and ROS1 fusions: ABL1, AKT1, AKT3, ALK, APC, AR, ATM, AXL, BRAF, BRCA1, BRCA2, CCND1, CDH1, CDK4, CDK6, CDKN2A, CEBPA, CSF1R, CTNNB1, DDR2, EGFR, ERBB2, ERBB3, ERBB4, ERG, ESR1, ETV1, ETV4, ETV5, EZH2, FANCA, FANCC, FANCF, FANCG, FBXW7, FGFR1, FGFR2, FGFR3, FGFR4, FLT3, FOXL2, GNA11, GNAQ, GNAS, HNF1A, HRAS, IDH1, IDH2, JAK1, JAK2, JAK3, KDR, KIT, KRAS, MAP2K1, MAP2K2, MAP2K4, MET, MLH1, MPL, MTOR, MYC, MYCN, NOTCH1, NPM1, NRAS, NTRK1, NTRK2, NTRK3, PDGFRA, PIK3CA, PIK3R1, PPARG, PTEN, PTPN11, RAF1, RB1, RET, ROS1, RUNX1, SMAD4, SMARCB1, SMO, SRC, STK11, TP53, VHL, WT1
Intended useSomatic profiling from blood. A negative liquid biopsy does not exclude a tumour variant.
Approximate turnaroundConfirmed when you enquire
Report typeNGS report with sequencing quality metrics, SNV/indel, fusion and copy-number sections
Ordering requirementsConfirmed when you enquire
PriceConfirmed when you enquire

Turnaround, price and sample requirements are confirmed when you enquire, so you never rely on an outdated figure. Whether this test is appropriate is a decision for the treating oncologist.

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