What is NGS testing for cancer?
A plain-language guide to next-generation sequencing (NGS) in cancer care: what it is, what samples are used, what a report can show and why a doctor should interpret it.
Clinical review: pending · General information, not medical advice
NGS in one paragraph
Next-generation sequencing (NGS) is a laboratory method that reads many pieces of DNA at the same time. In cancer care it is used to look at selected genes, or larger parts of the genome, for changes called variants that may be relevant to a person's disease.
How is it different from older tests?
Older molecular tests often looked at one gene, or a small number of genes, at a time. NGS can examine many genes in a single run. This is why a doctor may choose it when several genes could matter for the clinical question.
What sample is used?
It depends on the test. Common sample types include tumour tissue and blood. Each test has its own requirements for sample type, quantity and handling, and these are confirmed before anything is collected.
What can a report tell you, and what can it not?
A report usually lists the variants found, how each is classified and the evidence behind it. It may point to information that is relevant to a treatment discussion. It cannot promise a treatment option, a response or an outcome, and many reports contain no finding that changes the plan.
Who should interpret the result?
Your treating oncologist, who knows your full clinical picture. Please do not change or stop any treatment based on a report without speaking to your doctor.
Next step
Prebooking for NGS genomic testing through DNA by MedXplorer360 opens soon. You can join the priority list on this site; joining is free and involves no payment.
Prebooking opens soon. Join the priority list. It is free and involves no payment.
Join the prebooking list